Pediatric partial-thickness burns at function-critical sites require rapid epithelialization to limit hypertrophic scarring and contracture. We assessed outcomes after tangential dermabrasion with application of cryopreserved human amnion (hAM).
Retrospective single-center cohort of children < 18 years treated from 2013 to June 2024. Standard care included early tangential dermabrasion and hAM fixation. Primary endpoint was days from injury to ≥ 95% re-epithelialization. Secondary endpoints included length of stay, autografting, hAM-related adverse events, hypertrophic scarring, contracture, and Patient and Observer Scar Assessment Scale (POSAS) at 12 months.
Conclusions
After standardized dermabrasion, cryopreserved hAM supported closure within the expected healing window. Time to epithelialization remained the main determinant of scar outcomes.
